Formulation: A crystalline solid
Formal Name: N-[3-chloro-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)phenyl]-5-fluoro-2-methyl-benzamide
Purity: ≥97%
Formula Markup: C27H21ClFN3O2
Formula Weight: 473,9
Shelf life (days): 1460
CAS Number: 168079-32-1
Notes: Lixivaptan is a nonpeptide antagonist of vasopressin V2 receptors (Ki = 2.3 nM).{34309} It is 100-fold selective for V2 over V1a.{27294} Formulations containing lixivaptan decrease urinary excretion of aquaporin-2 in patients with chronic heart failure and increase serum sodium levels in patients with hyponatremia due to congestive heart failure.{34307,34308}