LN6023 (hydrochloride)

Formulation: A solid

Formal Name: N-(tert-butyl)-1-(3-((7-ethyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)amino)propyl)piperidine-4-carboxamide, dihydrochloride

Purity: ≥98%

Formula Markup: C20H32N6O2S • 2HCl

Formula Weight: 493,5

Shelf life (days): 1460

Notes: LN6023 is an agonist of chemokine (C-X-C motif) receptor 7 (CXCR7).{72231} It induces β-arrestin recruitment in a reporter assay using HEK293T cells expressing human CXCR7 (EC50 = 3.5 µM) but not in HEK293T cells expressing human CXCR4. LN6023 (100 µM) reduces surface levels of P-selectin in isolated and washed human platelets.

• SKU: CAY40287-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40287-10
• Package Unit: 10 mg
• Quantity Unit: STK