LPA2 Antagonist 1, CAS 1017606-66-4

Formulation: A crystalline solid

Formal Name: N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-methylethyl]-7-methyl-thieno[3,2-d]pyrimidin-4-amine

Purity: ≥98%

Formula Markup: C20H23Cl2N5O2S2

Formula Weight: 500,5

Shelf life (days): 1460

CAS Number: 1017606-66-4

Notes: LPA2 antagonist 1 is an antagonist of lysophosphatidic acid receptor 2 (LPA2; IC50 = 17 nM).{43178} It is selective for LPA2 over LPA1 and LPA3 (IC50s = >50 μM). LPA2 antagonist 1 inhibits HGF-induced phosphorylation of ERK and proliferation of HCT116 colon cancer cells in a concentration-dependent manner.

• SKU: CAY22051-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 22051-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK