LY2955303, CAS 1433497-19-8

LY2955303, CAS 1433497-19-8
SKU
CAY25833-1
Packaging Unit
1 mg
Manufacturer
Cayman Chemical

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Formulation: A crystalline solid

Formal Name: 4-[5-[3,5-bis(1,1-dimethylethyl)phenyl]-1-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-1H-pyrazol-3-yl]-benzoic acid

Purity: ≥95%

Formula Markup: C36H42N4O3

Formula Weight: 578,7

Shelf life (days): 1460

CAS Number: 1433497-19-8

Notes: LY2955303 is a potent antagonist of retinoic acid receptor γ (RARγ; Ki = 1.1 nM).{42717} It is selective for RARγ over RARα and RARβ (Kis = >1,700 and >2,980 nM, respectively). LY2955303 reduces differential weight bearing between the contralateral and ipsilateral limbs in a rat model of monoiodoacetate-induced osteoarthritis (ED50 = 0.72 mg/kg).
More Information
SKU CAY25833-1
Manufacturer Cayman Chemical
Manufacturer SKU 25833-1
Green Labware No
Package Unit 1 mg
Quantity Unit STK
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