Lys-(Des-Arg9, Leu8)-Bradykinin (trifluoroacetate salt)

Formulation: A solid

Formal Name: 9-L-leucine-1-9-kallidin, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C47H75N13O11 • XCF3COOH

Formula Weight: 998,2

Shelf life (days): 1460

Notes: Lys-(Des-Arg9, Leu8)-Bradykinin is a bradykinin B1 receptor antagonist (Ki = 0.43 nM for the rabbit aorta receptor).{65251} It is selective for the bradykinin B1 over the B2 receptor (Ki = >10 µM for the rabbit ileum receptor).{65252} Lys-(Des-Arg9, Leu8)-Bradykinin inhibits contractions induced by the bradykinin B1 receptor agonist Des-Arg9-bradykinin (Item No. 31136) in isolated rabbit aortic rings (pA2 = 8.54).{65253} Intraperitoneal administration of Lys-(Des-Arg9, Leu8)-bradykinin (5 mg/kg per day for three days) reduces increases in paw edema in a rat model of arthritis induced by peptidoglycan-polysaccharide (PGPS).{65254}

• SKU: CAY35462-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35462-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Reinstoffe