MCOPPB (hydrochloride hydrate)

Formulation: A crystalline solid

Formal Name: 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole, trihydrochloride, hydrate

Purity: ≥98%

Formula Markup: C26H40N4 • 3HCl [XH2O]

Formula Weight: 536

Shelf life (days): 1460

Notes: The nociceptin/orphanin FQ peptide (NOP, ORL1, or OP4) receptor is a member of the opioid family of receptors that integrates the emotional components of anxiety, fear, and stress. MCOPPB is a potent agonist for the NOP receptor (pKi = 10.1, EC50 = 0.39 nM) with 12-, 270-, and >1,000-fold selectivity over the μ-, κ-, and δ-opioid receptors.{22070,22071} In rodents, MCOPPB at 10 mg/kg, p.o. produces potent anxiolytic effects, without inhibiting memory or motor function or inducing sedative side effects.{22070} This product is intended for research purposes only.

• SKU: CAY12037-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 12037-10
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Reinstoffe