Formulation: A solid
Formal Name: 3,5-dimethyl-4-(methylthio)phenyl (methyl-d3)carbamate
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C11H12D3NO2S
Formula Weight: 228,3
Shelf life (days): 1460
CAS Number: 1581694-94-1
Notes: Methiocarb-d3 is intended for use as an internal standard for the quantification of methiocarb (Item No. 25627) by GC- or LC-MS. Methiocarb is a carbamate pesticide.{43318} It inhibits the activity of acetylcholinesterase (AChE) from methiocarb-resistant and -sensitive western flower thrips (F. occidentalis; IC50s = 0.43 and 2.1 µM, respectively) and is toxic to the same strains (LC50s = 31.1 and 3.26 ppm for the resistant- and sensitive strains, respectively). Methiocarb is also toxic to the land snail (M. obstructa; LD50 = 27.4 μg/animal) and induces 94% mortality in citrus mites (A. pelekassi) when used at a concentration of 0.5 ppm.{43317,43319} It is an estrogen receptor α (ERα) and ERβ agonist (EC20s = 19.87 and 20.24 μM, respectively) and androgen receptor antagonist (IC50 = 13.89 μM) in cell-based reporter assays.{43321} It is toxic to juvenile rainbow trout and guppies with LC50 values of 0.795 and 1.482 mg/L, respectively, at 48 hours of exposure.{43322} Formulations containing methiocarb have been used in the control of mollusks, mites, and insects in residential and commercial settings.
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