Formulation: A crystalline solid
Formal Name: (1α,2β,4β,5α,7β)-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane, monobromide
Purity: ≥98%
Formula Markup: C18H24NO4 • Br
Formula Weight: 398,3
Shelf life (days): 1460
CAS Number: 155-41-9
Notes: Methylscopolamine is an antagonist of muscarinic acetylcholine receptors (Kds = 0.25, 0.37, 0.23, 0.22, and 0.3 nM for M1-5 respectively).{37295} It inhibits oxotremorine-induced gastric ulcer formation and pupillary light reflex in rats (ED50s = 0.4 and 3.6 μg/kg, respectively).{37296} It also increases pupil diameter in rats with an ED200 value of 1.8 μg/kg. Formulations containing methylscopolamine have been used for the treatment of peptic ulcers, intestinal spasms, and motion sickness.