MK-3697, CAS 1224846-01-8

Formulation: A solid

Formal Name: N-[(5,6-dimethoxy-2-pyridinyl)methyl]-5′-methyl-5-(2-thiazolyl)-[2,3′-bipyridine]-4-carboxamide

Purity: ≥98%

Formula Markup: C23H21N5O3S

Formula Weight: 447,5

Shelf life (days): 1460

CAS Number: 1224846-01-8

Notes: MK-3697 is an orexin receptor 2 (OX2R) antagonist (Ki = 1.1 nM).{61642} It is selective for OX2R over OX1R (Ki = 3,600 nM). MK-3697 decreases active awake time and increases slow wave sleep (SWS) and rapid eye movement (REM) sleep in mice when administered at a dose of 100 mg/kg. It also decreases active awake time and increases phase II SWS in dogs.

• SKU: CAY34718-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34718-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK