ML-133 (hydrochloride), CAS 1222781-70-5

Formulation: A crystalline solid

Formal Name: N-[(4-methoxyphenyl)methyl]-1-naphthalenemethanamine, monohydrochloride

Purity: ≥98%

Formula Markup: C19H19NO • HCl

Formula Weight: 313,8

Shelf life (days): 1460

CAS Number: 1222781-70-5

Notes: ML-133 is an inward-rectifier potassium channel 2 (Kir2) inhibitor (IC50s = 1.8, 2.8, 2,9, and 2.6 µM for Kir2.1, Kir2.2, Kir2.3, and Kir2.6, respectively).{61043} It is selective for Kir2 channels over Kir1.1 and Kir4.1 channels (IC50s = 33 and 76 µM, respectively). ML-133 (10 and 30 nmol/animal) prevents the development of dynamic, but not punctate, mechanical allodynia in a mouse model of spared nerve injury.{61040}

• SKU: CAY31232-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 31232-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK