ML-SA1, CAS 332382-54-4

Formulation: A crystalline solid

Formal Name: 2-[2-(3,4-dihydro-2,2,4-trimethyl-1(2H)-quinolinyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione

Purity: ≥98%

Formula Markup: C22H22N2O3

Formula Weight: 362,4

Shelf life (days): 1460

CAS Number: 332382-54-4

Notes: ML-SA1 is an agonist of transient receptor potential mucolipin 1 (TRPML1).{46901} It induces cytosolic calcium increases in HEK293T cells expressing surface-expressed mutant TRPML1 channels when used at a concentration of 10 µM. ML-SA1 activates TRPML1-mediated current (IML1) in isolated vacuoles that were enlarged by vacuolin-1 (Item No. 20425) prior to isolation from HEK293 cells expressing TRPML1. It also activates whole-endolysosome IML1 in primary murine macrophages.

• SKU: CAY29958-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29958-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK