MONNA, CAS 1572936-83-4

Formulation: A crystalline solid

Formal Name: 2-[(4-methoxy-2-naphthalenyl)amino]-5-nitro-benzoic acid

Purity: ≥98%

Formula Markup: C18H14N2O5

Formula Weight: 338,3

Shelf life (days): 1460

CAS Number: 1572936-83-4

Notes: MONNA is a selective inhibitor of anoctamin-1 (ANO1; IC50 = 0.08 µM in Xenopus oocytes), a calcium-activated chloride channel (CaCC).{34636} It is selective for ANO1 over the chloride channels bestrophin-1, chloride channel protein 2, and cystic fibrosis transmembrane conductance regulator up to 10 µM. MONNA (10 µM) induces full vasorelaxation of preconstricted mouse isolated mesenteric arteries in the presence or absence of chloride.{34635} It also hyperpolarizes isolated rat mesenteric arteries under resting conditions.

• SKU: CAY21917-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21917-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK