Moperone, CAS 1050-79-9

Formulation: A solid

Formal Name: 1-(4-fluorophenyl)-4-[4-hydroxy-4-(4-methylphenyl)-1-piperidinyl]-1-butanone

Purity: ≥98%

Formula Markup: C22H26FNO2

Formula Weight: 355,5

Shelf life (days): 1460

CAS Number: 1050-79-9

Notes: Moperone is a dopamine D2, D3, and D4 receptor antagonist (Kis = 0.7, 14, and 27 nM, respectively, in NIH3T3 cells expressing the human receptors).{25512} It also inhibits E. electricus acetylcholinesterase (AChE; Ki = 120 µM) and is a histamine H1 receptor inverse agonist (IC50 = 794 nM for the human receptor).{51300,51301} Intraocular administration of moperone (0.5% w/v) induces ocular hypotension in normotensive rabbits.{51302} Formulations containing moperone have been used in the treatment of schizophrenia, psychosis, epilepsy, and alcohol withdrawal syndrome.

• SKU: CAY21968-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21968-5
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe