MSX-122, CAS 897657-95-3

Formulation: A crystalline solid

Formal Name: N1,N4-di-2-pyrimidinyl-1,4-benzenedimethanamine

Purity: ≥98%

Formula Markup: C16H16N6

Formula Weight: 292,3

Shelf life (days): 1460

CAS Number: 897657-95-3

Notes: MSX-122 is a small molecule partial antagonist of C-X-C chemokine 4 (CXCR4; IC50 = ~10 nM).{38354} It reduces inflammation and infiltration of CXCR4+ cells in a dextran sulfate (Item No. 23250) model of experimental colitis in mice. Specifically, it prevents the production of TNF-α, IL-1β, and IL-6. MSX-122 also reduces TNF-α secretion by macrophages infected with patient-derived invasive E. coli. It decreases metastases in mouse models utilizing MDA-MB-231 breast cancer or 686LN-Ms squamous cell carcinoma cells injected intravenously or OMM2.3 melanoma cells inoculated into the eye.

• SKU: CAY23426-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 23426-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK