N-desmethyl Trimipramine, CAS 2293-21-2

Formulation: A solution in methanol

Formal Name: 10,11-dihydro-N,β-dimethyl-5H-dibenz[b,f]azepine-5-propanamine

Purity: ≥95%

Formula Markup: C19H24N2

Formula Weight: 280,4

Shelf life (days): 730

CAS Number: 2293-21-2

Notes: N-desmethyl Trimipramine is an active metabolite of the tricyclic antidepressant trimipramine (Item No. 15921).{67010} It inhibits the norepinephrine transporter (NET), serotonin (5-HT) transporter (SERT), and dopamine transporter (DAT; IC50s = 2.92, 6.22, and 29.5 µM, respectively) as well as organic cation transporter 1 (OCT1) and OCT2 (IC50s = 3.19 and 10.4 µM, respectively) in HEK293 cells expressing the human transporters.

• SKU: CAY34982-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34982-500
• Green Labware: No
• Package Unit: 500 µg
• Quantity Unit: STK
• Application: Reinstoffe