N-didesmethyl Loperamide, CAS 66164-06-5

Formulation: A solid

Formal Name: 4-(4-chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinebutanamide

Purity: ≥95%

Formula Markup: C27H29ClN2O2

Formula Weight: 449

Shelf life (days): 1460

CAS Number: 66164-06-5

Notes: N-didesmethyl Loperamide is an active metabolite of the peripheral μ1-opioid receptor agonist loperamide.{67472} It inhibits electricity-induced contractions in isolated guinea pig myenteric plexus (IC50 = 370 nM).{67473} N-didesmethyl Loperamide sensitizes a chloroquine-resistant P. falciparum strain to chloroquine (EC50 = 482 nM) without inducing toxicity in A-10 vascular smooth muscle cells (IC50 = >10,000 nM).{67474}

• SKU: CAY39559-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39559-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK