Formulation: A crystalline solid
Formal Name: N2-[(9Z)-1-oxo-9-octadecen-1-yl]-L-glutamine
Purity: ≥95%
Formula Markup: C23H42N2O4
Formula Weight: 410,6
Shelf life (days): 730
CAS Number: 247150-73-8
Notes: N-Oleoyl glutamine is an endogenous N-acyl amine.{31656,49699} It is both formed and degraded by peptidase M20 domain-containing 1 (PM20D1), a factor secreted by thermogenic adipose cells. N-Oleoyl glutamine (50 µM) induces mitochondrial uncoupling to increase respiration in C2C12 cells by 64%.{49700} It inhibits capsaicin-induced calcium flux in HEK293A cells co-transfected with transient receptor potential vanilloid 1 (TRPV1) and red fluorescent protein (RFP).{49699} N-Oleoyl glutamine (100 mg/kg) reduces the number of acetic acid-induced abdominal constrictions, as well as formalin-induced paw licking in mice.