Naloxone benzoylhydrazone, CAS 119630-94-3

Formulation: A solid

Formal Name: 2-[(5α)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)ylidene]hydrazide, benzoic acid

Purity: ≥98%

Formula Markup: C26H27N3O4

Formula Weight: 445,5

Shelf life (days): 1460

CAS Number: 119630-94-3

Notes: Naloxone benzoylhydrazone is an antagonist of μ-, κ1-, and δ-opioid receptors (pA2s = 8.82, 7.45, and 7.76, respectively, for the mouse receptors).{69496} It is also an agonist of the κ3-opioid receptor (IC50 = 0.7 nM for the guinea pig receptor). Naloxone benzoylhydrazone (1 µg/animal, i.c.v.) inhibits increases in the latency to tail withdrawal induced by the μ-opioid receptor agonist DAMGO (Item No. 21553) in a hot plate assay in mice.{69497} It increases food intake in rats when intracerebrally administered at doses of 0.1, 1, and 20 µg/animal.{69498}

• SKU: CAY39827-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39827-10
• Package Unit: 10 mg
• Quantity Unit: STK