NBQX, CAS 118876-58-7

Formulation: A solid

Formal Name: 1,2,3,4-tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide

Purity: ≥98%

Formula Markup: C12H8N4O6S

Formula Weight: 336,3

Shelf life (days): 1460

CAS Number: 118876-58-7

Notes: NBQX is an antagonist of AMPA and kainate receptors (IC50s = 0.15 and 4.8 µM, respectively).{23787} It is selective for these receptors over NMDA receptors (IC50 = ≥90 µM). In vivo, NBQX (20 mg/kg) increases the latency to seizures, decreases the duration of seizures, and reduces seizure severity in a rat model of epilepsy induced by pentylenetetrazole (PTZ; Item No. 18682).{51462} It also suppresses relapse phase nicotine self-administration in rats.{51461}

• SKU: CAY38281-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38281-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK