Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)

Formulation: A lyophilized powder

Purity: ≥95%

Formula Markup: C175H269N53O54S • XCF3COOH

Formula Weight: 4011,4

Shelf life (days): 1460

Notes: Neuropeptide Y (NPY) (3-36) is a C-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion.{5565} NPY (3-36) is an endogenous peptide produced by cleavage of NPY by dipeptidyl peptidase 4 (DPP-4).{41604,41605} It binds selectively to the NPY receptor Y2 (Ki = 0.41 nM in CHP 234 cells) over the Y1 receptor, where it does not bind at concentrations up to 1 µM. NPY (3-36) (0.1 nM) increases migration of human umbilical vein endothelial cells (HUVECs) by 80% after 12 hours in an in vitro wound closure assay.{41606} NPY (3-36) corresponds to residues 3-36 of the human and rat protein sequence.

• SKU: CAY24713-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 24713-500
• Green Labware: No
• Package Unit: 500 µg
• Quantity Unit: STK