Neuropeptide Y (porcine, bovine) (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-tyrosyl-L-prolyl-L-seryl-L-lysyl-L-prolyl-L-α-aspartyl-L-asparaginyl-L-prolylglycyl-L-α-glutamyl-L-α-aspartyl-L-alanyl-L-prolyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-leucyl-L-alanyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-isoleucyl-L-asparaginyl-L-leucyl-L-isoleucyl-L-threonyl-L-arginyl-L-glutaminyl-L-arginyl- L-tyrosinamide, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C190H287N55O57 • XCF3COOH

Formula Weight: 4253,7

Shelf life (days): 1460

Notes: Neuropeptide Y (NPY) is a neuropeptide involved in appetite, vasoconstriction, cardiac contractility, and intestinal secretion and an agonist of the NPY receptors Y1, Y2, and Y5.{5565,41608} It is expressed throughout the body.{5565} NPY selectively inhibits forskolin-induced cAMP accumulation in L-M(TK-) cells expressing rat Y1 or Y2 and HEK293 cells expressing rat Y5 over L-M(TK-) cells expressing rat Y4 receptors (EC50s = 0.15, 2.7, 0.66, and >1,000 nM, respectively).{41608} It increases perfusion pressure in isolated guinea pig heart (EC30 = 1.3 nM).{51408} Intracerebroventricular administration of NPY (300 pmol/animal) increases food intake in rats.{41608}

• SKU: CAY36715-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36715-1
• Package Unit: 1 mg
• Quantity Unit: STK