(−)-Nicotine, CAS 54-11-5

Formulation: An oil

Formal Name: 3-[(2S)-1-methyl-2-pyrrolidinyl]-pyridine

Purity: ≥95%

Formula Markup: C10H14N2

Formula Weight: 162,2

Shelf life (days): 1460

CAS Number: 54-11-5

Notes: (–)-Nicotine is an alkaloid that has been found in tobacco.{26727} It is an agonist at neuronal nicotinic acetylcholine receptors (nAChRs) and binds to α3β4 and α4β2 subunit-containing nAChRs with Ki values of 481 and 11.1 nM, respectively.{26727,18814} Chronic exposure to (–)-nicotine results in increased expression of certain nAChRs, particularly α4β2 subunit-containing nAChRs.{48631} (–)-Nicotine has addictive properties.{18814,48631} Formulations containing (–)-nicotine have been used as smoking cessation aids for the relief of nicotine withdrawal symptoms.

• SKU: CAY29138-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29138-25
• Green Labware: No
• Package Unit: 25 g
• Quantity Unit: STK