Formulation: A crystalline solid
Formal Name: 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione
Purity: ≥98%
Formula Markup: C12H10F3N3O4
Formula Weight: 317,2
Shelf life (days): 1460
CAS Number: 63612-50-0
Notes: Nilutamide is a non-steroidal antiandrogen that is an antagonist of the androgen receptor.{41485} It reverses testosterone-induced increases in cell proliferation with an IC50 value of 412 nM in mouse mammary carcinoma cells in vitro.{41484} It has antiandrogenic activity in both intact and castrated rats, inhibiting testosterone propionate-induced prostate growth when administered at a dose of 2.5 mg/kg.{41486} Formulations containing nilutamide have been used in combination with surgical castration in the treatment of metastatic prostate cancer.