Formulation: A solid
Formal Name: 4-(2-amino-1-hydroxyethyl-1,2,2-d3)-1,2-benzene-3,4,6-d3-diol, monohydrochloride
Purity: ≥99% (deuterated forms d1-d6)
Formula Markup: C8H5D6NO3 • HCl
Formula Weight: 211,7
Shelf life (days): 1460
CAS Number: 1219803-04-9
Notes: (±)-Norepinephrine-d6 is intended for use as an internal standard for the quantification of norepinephrine (Item No. 35580) by GC- or LC-MS. (±)-Norepinephrine is a racemic mixture of the endogenous neurotransmitter (–)-norepinephrine (Item No. 16673) and (+)-norepinephrine. It induces cAMP accumulation in rat cerebral cortical membranes when used at concentrations ranging from 1 to 100 µM.{67104} (±)-Norepinephrine induces contraction of bovine anterior cerebral, middle cerebral, and internal carotid arterial strips (EC50s = 0.91, 0.92, and 0.87 µM, respectively) but induces relaxation of bovine posterior cerebral arterial strips (EC50 = 0.95 µM).{67105} Formulations containing (±)-norepinephrine have been used for the restoration of blood pressure in acute hypotensive states.
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