(±)-Nornicotine-d4, CAS 66148-18-3

Formulation: A neat oil

Formal Name: 5-(2-pyrrolidinyl)-pyridine-2,3,4,6-d4

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C9H8D4N2

Formula Weight: 152,2

Shelf life (days): 1460

CAS Number: 66148-18-3

Notes: (±)-Nornicotine-d4 is intended for use as an internal standard for the quantification of (±)-nornicotine (Item No. 20505) by GC- or LC-MS. (±)-Nornicotine is an active metabolite of nicotine (Item No. 16535) and a nicotinic acetylcholine receptor (nAChR) agonist.{34465} It induces currents in Xenopus oocytes expressing human α7 nAChRs or α6 subunit-containing nAChRs (EC50s = 17 and 3.7 µM, respectively). (±)-Nornicotine promotes cell migration and destabilizes cell-cell junctions in EA.hy926 endothelial cells.{34463} It is self-administered in rats.{34462,34464}

• SKU: CAY35242-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35242-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: GC-MS, LC-MS, Isotopenmarkierung