O-desmethyl Galantamine, CAS 60755-80-8

Formulation: A solid

Formal Name: (4aS,6R,8aS)-4a,5,9,10,11,12-hexahydro-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepine-3,6-diol

Purity: ≥90%

Formula Markup: C16H19NO3

Formula Weight: 273,3

Shelf life (days): 1460

CAS Number: 60755-80-8

Notes: O-desmethyl Galantamine is an active metabolite of the alkaloid galantamine (Item No. 17559).{62642} It is formed from galantamine by the cytochrome P450 (CYP) isoform CYP2D6.{47974} O-desmethyl Galantamine inhibits erythrocyte and brain acetylcholinesterase (AChE) and plasma butyrylcholinesterase (BChE; IC50s = 0.12, 0.5, and 24 µM, respectively). It also prevents decreases in the viability of SH-SY5Y cells induced by hydrogen peroxide, amyloid-β (25-35) (Item No. 24155), or cobalt chloride when used at concentrations ranging from 6.25 to 100 µM.{67000}

• SKU: CAY35080-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35080-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Reinstoffe