Formulation: A solid
Formal Name: 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethenyl]-benzene
Purity: ≥95%
Formula Markup: C14H8Cl4
Formula Weight: 318
Shelf life (days): 1460
CAS Number: 3424-82-6
Notes: o,p'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT.{39801} It accumulates in smallmouth buffalo, channel catfish, and largemouth bass as well as sediment in the Huntsville Spring Branch-Indian Creek tributary system surrounding a DDT manufacturing plant where it is considered a persistent organic pollutant (POP). o,p'-DDE inhibits estrogen binding to rainbow trout estrogen receptors (rtERs) with an IC50 value of 3.2 μM.{12991} It induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles.{39802} In ovo exposure to o,p'-DDE increases degeneration of ovarian follicles and reduces testicular size in Japanese medaka (O. latipes).{39803}
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