Formulation: A solid
Formal Name: 2-[4-amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]-benzenemethanol
Purity: ≥98%
Formula Markup: C17H17N5O
Formula Weight: 307,3
Shelf life (days): 1460
CAS Number: 1309198-71-7
Notes: Ogerin is a positive allosteric modulator of G protein-coupled receptor 68 (GPR68).{60501} It increases proton-induced cAMP production in HEK293T cells expressing the human receptor in a reporter assay. Ogerin inhibits proton-mediated calcium release in the same cells when used at a concentration of 10 µM. It impairs contextual, but not cued, fear conditioning in wild-type, but not Gpr68 knockout, mice when administered at a dose of 10 mg/kg.