Oleanolic Acid Acrylate, CAS 1975976-24-9

Formulation: A crystalline solid

Formal Name: 3β-[(1-oxo-2-propen-1-yl)oxy]-olean-12-en-28-oic acid

Purity: ≥95%

Formula Markup: C33H50O4

Formula Weight: 510,7

Shelf life (days): 730

CAS Number: 1975976-24-9

Notes: Oleanolic acid acrylate (OAA) is an agonist of the serotonin (5-HT) receptor subtype 5-HT1A and a derivative of oleanolic acid (Item No. 11726).{50366} It acts as an agonist at the 5-HT1A receptor in mouse hippocampal homogenates in a [35S]GTPγS binding assay (EC50 = 0.79 µM). It is also a selective inhibitor of MAO-A over MAO-B (IC50s = 48.8 µM and >100 µM, respectively). In mice, OAA (10 mg/kg) reduces immobility in the forced swim test and increases the number of crossings and time spent at the center in the open field test, indicating anti-depressant-like and anxiolytic activities.

• SKU: CAY27206-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 27206-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK