Formulation: A crystalline solid
Formal Name: 3β-[(1-oxo-2-propen-1-yl)oxy]-olean-12-en-28-oic acid
Purity: ≥95%
Formula Markup: C33H50O4
Formula Weight: 510,7
Shelf life (days): 730
CAS Number: 1975976-24-9
Notes: Oleanolic acid acrylate (OAA) is an agonist of the serotonin (5-HT) receptor subtype 5-HT1A and a derivative of oleanolic acid (Item No. 11726).{50366} It acts as an agonist at the 5-HT1A receptor in mouse hippocampal homogenates in a [35S]GTPγS binding assay (EC50 = 0.79 µM). It is also a selective inhibitor of MAO-A over MAO-B (IC50s = 48.8 µM and >100 µM, respectively). In mice, OAA (10 mg/kg) reduces immobility in the forced swim test and increases the number of crossings and time spent at the center in the open field test, indicating anti-depressant-like and anxiolytic activities.