ORG 12962 (hydrochloride), CAS 210821-63-9

Formulation: A solid

Formal Name: 1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine, monohydrochloride

Purity: ≥98%

Formula Markup: C10H11ClF3N3 • HCl

Formula Weight: 302,1

Shelf life (days): 730

CAS Number: 210821-63-9

Notes: ORG 12962 is an agonist of the serotonin (5-HT) receptor subtype 5-HT2C with an EC50 value of 97.72 nM in a FLIPR-based intracellular calcium assay using CHO-K1 cells expressing the human receptor.{52211} It is selective for 5-HT2C over 5-HT2A and 5-HT2B receptors (EC50s = 419.87 and 524.81 nM, respectively). ORG 12962 (1 and 3.2 mg/kg) has anti-aversive effects in a rat model of panic anxiety induced by dorsolateral periaqueductal gray matter (dPAG) stimulation.{48814}

• SKU: CAY27675-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 27675-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK