Formal Name: glycyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalanine, trifluoroacetate salt
Purity: ≥95%
Formula Markup: C33H45N7O8 • XCF3COOH
Formula Weight: 667,8
Shelf life (days): 1460
Notes: PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4; EC50 = 30 μM in Xenopus oocytes expressing human PAR4 receptors) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence.{45154} It induces calcium release in wild-type and PAR3-/- mouse platelets and in human platelets but has no activity in Xenopus oocytes expressing human PAR1. PAR4 (1-6) also triggers [3H]inositol phosphate release from KOLF cells expressing human PAR4.{47230}