Paraherquamide A, CAS 77392-58-6

Formulation: A powder

Formal Name: (1'R,5'aS,7'R,8'aS,9'aR)-2',3',8'a,9'-tetrahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizine]-9,10'(10H)-dione

Purity: ≥95%

Formula Markup: C28H35N3O5

Formula Weight: 493,6

Shelf life (days): 1460

CAS Number: 77392-58-6

Notes: Paraherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei.{47167} It binds to acetylcholine receptors (IC50 = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist.{47167,47168} Paraherquamide A is toxic to C. elegans (LD50 = 2.5 µg/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg.{47169,47170} It is toxic to mice (LD50 = 14.9 mg/kg).{47171}

• SKU: CAY26685-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 26685-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK