(+)-PD 128907 (hydrochloride), CAS 300576-59-4

Formulation: A crystalline solid

Formal Name: 3,4,4aR,10bR-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol, monohydrochloride

Purity: ≥98%

Formula Markup: C14H19NO3 • HCl

Formula Weight: 285,8

Shelf life (days): 1460

CAS Number: 300576-59-4

Notes: (+)-PD 128907 is a potent agonist of the dopamine 3 (D3) receptor (Ki = 1 nM).{33953,33956} It shows selectivity for D3 over D2 and D4 receptors (Kis = 1.2 and 7 µM, respectively).{33953} Low doses of (+)-PD 128907 (13 µg/kg, s.c.) reduce spontaneous locomotor activity in rats.{33954} It blocks stereotypy induced by the NMDA receptor antagonist (+)-MK-801 (Item No. 10009019) in mice.{33957} (+)-PD 128907 is used in animal models to study the role of the D3 receptor in nervous system disorders, such as schizophrenia, Parkinson’s disease, and depression.{31907,33955}

• SKU: CAY21235-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21235-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK