PF-998425, CAS 1076225-27-8

Formulation: A solid

Formal Name: 4-[(1R,2R)-2-hydroxycyclohexyl]-2-(trifluoromethyl)-benzonitrile

Purity: ≥98%

Formula Markup: C14H14F3NO

Formula Weight: 269,3

Shelf life (days): 1460

CAS Number: 1076225-27-8

Notes: PF-998425 is a non-steroidal androgen receptor antagonist (IC50 = 43 nM in a cell-based assay).{57126} It binds to the androgen receptor (IC50 = 37 nM in a radioligand binding assay) and is selective for the androgen receptor over the progesterone receptor (IC50 = >10,000 nM). Topical administration of PF-998425 (3% twice per day) increases hair growth in a mouse model of hair growth, as well as reduces ear sebum in male Syrian golden hamsters (ED50 = 0.4% twice per day).

• SKU: CAY31442-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 31442-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK