Phellopterin, CAS 2543-94-4

Formulation: A solid

Formal Name: 7-butyl-5-hydroxy-2-methyl-2-(4-methyl-3-penten-1-yl)-2H-1-benzopyran-6-carboxylic acid

Purity: ≥98%

Formula Markup: C17H16O5

Formula Weight: 300,3

Shelf life (days): 1460

CAS Number: 2543-94-4

Notes: Phellopterin is a furanocoumarin that has been found in A. dahurica and has diverse biological activities.{67567,64084,67568} It is an antagonist of GABAA receptors (IC50 = 360 nM for the rat receptor).{67567} Phellopterin (20 µM) decreases LPS-induced secretion of prostaglandin E2 (PGE2; Item No. 14010) from primary rat peritoneal macrophages.{64084} Topical application of phellopterin (1.2 µg/g) accelerates wound healing in a mouse model of diabetes induced by streptozotocin (Item No. 13104).{67568} It increases the levels of mRNA encoding sirtuin 1 (Sirt1) and decreases mRNA encoding intracellular adhesion molecule-1 (Icam-1) in epithelium isolated from mice in the same model.

• SKU: CAY38965-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38965-1
• Package Unit: 1 mg
• Quantity Unit: STK