Picrotin, CAS 21416-53-5

Formulation: A crystalline solid

Formal Name: (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-3,6-methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione

Purity: ≥98%

Formula Markup: C15H18O7

Formula Weight: 310,3

Shelf life (days): 1460

CAS Number: 21416-53-5

Notes: Picrotin is a natural picrotoxane that antagonizes glycine receptors (GlyRs; IC50s = 57 and 117 µM for α1 and α2 homodimeric GlyRs, respectively).{33999,72055} It also inhibits α3 homodimeric GlyRs.{34001} Picrotin is inactive in inhibiting γ-aminobutyric acid (GABA) type A and type C receptors. Picrotin occurs in the natural plant-derived poison picrotoxin (Item No. 20771), equimolar with picrotoxinin.

• SKU: CAY21870-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21870-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK