Pioglitazone Ketone, CAS 146062-45-5

Formulation: A solid

Formal Name: 5-[[4-[2-(5-acetyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione

Purity: ≥98%

Formula Markup: C19H18N2O4S

Formula Weight: 370,4

Shelf life (days): 1460

CAS Number: 146062-45-5

Notes: Pioglitazone ketone is an active metabolite of the PPARγ agonist pioglitazone (Item Nos. 71745 / 10028 / 22263).{49141,49142,9838} Formation of pioglitazone ketone occurs primarly through cytochrome P450 (CYP) isoform CYP2C8-mediated metabolism of pioglitazone.{49141,49142} Pioglitazone ketone (100 mg/kg in the diet) reduces blood glucose levels in a KKAy mouse model of type 2 diabetes.{9838}

• SKU: CAY28044
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28044-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK