Formulation: A solid
Formal Name: 2-oxo-1-pyrrolidine-3,3,4,4,5,5-d6-acetamide
Purity: ≥99% deuterated forms (d1-d6)
Formula Markup: C6H4D6N2O2
Formula Weight: 148,2
Shelf life (days): 1460
CAS Number: 2907016-93-5
Notes: Piracetam-d6 is intended for use as an internal standard for the quantification of piracetam by GC- or LC-MS. Piracetam is a nootropic cyclic GABA derivative.{32770} It is a positive allosteric modulator of AMPA receptors and enhances binding of the NMDA antagonist MK-801 to rat forebrain membranes.{63173,63174} Piracetam (1 mM) protects against amyloid-β-induced decreases in the mitochondrial membrane potential, as well as decreases in neurite outgrowth in the presence of NGF, in PC12 rat adrenal medulla cells.{63172} It prevents scopolamine-induced amnesia in a passive avoidance test in mice when administered at a dose of 30 mg/kg.{63108} Formulations containing piracetam have been used in the treatment of myoclonus.
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