Formulation: A crystalline solid
Formal Name: 4-(2,3,6,9-tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid, monopotassium salt
Purity: ≥98%
Formula Markup: C14H13N4O5S • K
Formula Weight: 388,4
Shelf life (days): 1460
CAS Number: 409344-71-4
Notes: PSB-1115 is an antagonist of the adenosine A2B receptor (Ki = 53.4 nM).{40515} It is selective for A2B over A1 and A2A receptors, which have Ki values of 2,200 and 24,000 nM, respectively, and over the A3 receptor, which it inhibits only 14% at a concentration of 10 µM. PSB-1115 pre-treatment reduces relaxation of rat trachea induced by repeated dosing of the non-selective adenosine agonist NECA (Item No. 21420).{40516}