(R)-CPP, CAS 126453-07-4

Formulation: A crystalline solid

Formal Name: (2R)-4-(3-phosphonopropyl)-2-piperazinecarboxylic acid

Purity: ≥95%

Formula Markup: C8H17N2O5P

Formula Weight: 252,2

Shelf life (days): 1460

CAS Number: 126453-07-4

Notes: (R)-CPP is an NMDA receptor antagonist (Ki = 0.14 µM).{51092} It binds to NMDA receptors containing GluN2A, GluN2B, GluN2C, and GluN2D subunits with Ki values of 0.04, 0.3, 0.6, and 2 µM, respectively.{51093} It inhibits depolarization induced by NMDA in isolated hemisected frog spinal cord (pA2 = 6.56) and NMDA-induced sodium efflux from rat brain slices (pA2 = 6.2).{51092} (R)-CPP inhibits the clonic phase of sound-induced seizures in DBA/2 mice (ED50 = 65.8 µmol/kg) and the myoclonic phase of stroboscopic-induced seizures in P. papio photosensitive baboons (ED50 = 127 µmol/kg).{51094}

• SKU: CAY21569-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21569-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK