Notes: (R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol (Item No. 15418) metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide.{45165} (R)-Carvedilol glucuronide is formed via glucuronidation of (R)-carvedilol by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1 and UGT2B4. (S)-Carvedilol glucuronide is formed via glucuronidation of (S)-carvedilol by UGT2B4 and UGT2B7.