(R)-ZINC3573, CAS 2089389-15-9

Formulation: A solid

Formal Name: N,N-dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-3R-pyrrolidinamine

Purity: ≥95%

Formula Markup: C18H21N5

Formula Weight: 307,4

Shelf life (days): 1460

CAS Number: 2089389-15-9

Notes: (R)-ZINC3573 is an agonist of MAS-related G protein-coupled receptor family member X2 (MRGPRX2).{72505} It induces β-arrestin recruitment in a reporter assay using MRGPRX2-expressing HTLA cells and calcium mobilization in LAD 2 mast cells (EC50s = 0.74 and 1 µM, respectively). (R)-ZINC3573 is selective for MRGPRX2 over 21 other G protein-coupled receptors (GPCRs). It induces degranulation of LAD 2 mast cells in a concentration-dependent manner.

• SKU: CAY41312-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41312-10
• Package Unit: 10 mg
• Quantity Unit: STK