Formulation: A solid
Formal Name: α-cyclohexyl-α-hydroxy-benzeneacetic acid, 4-(ethylamino)-2-butyn-1-yl ester, monohydrochloride
Purity: ≥95%
Formula Markup: C20H27NO3 • HCl
Formula Weight: 365,9
Shelf life (days): 1460
CAS Number: 81039-77-2
Notes: rac-Desethyl oxybutynin is an active metabolite of the muscarinic acetylcholine receptor (mAChR) antagonist oxybutynin (Item No. 23825).{61451,61452,61453} rac-Desethyl oxybutynin is formed from oxybutynin by the cytochrome P450 (CYP) isoform CYP3A4.{61452} It binds to mAChRs in isolated rat bladder, submaxillary gland, heart, and colon with Ki values of 5.38, 3.12, 16, and 5.59 nM, respectively. rac-Desethyl oxybutynin (0.4 and 0.8 mg/kg) reduces micturition pressure in rats.{61453}