rac-trans-4-hydroxy Glyburide, CAS 23155-00-2

Formulation: A solid

Formal Name: 5-chloro-N-[2-[4-[[[[(trans-4-hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-benzamide

Purity: ≥98%

Formula Markup: C23H28ClN3O6S

Formula Weight: 510

Shelf life (days): 1460

CAS Number: 23155-00-2

Notes: rac-trans-4-hydroxy Glyburide is an active metabolite of the SUR1/Kir6.2 sulfonylurea inhibitor glyburide (Item No. 15009).{60355,60356} It is formed from glyburide by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9.{60355} rac-trans-4-hydroxy Glyburide inhibits glyburide binding to rat brain synaptosomes at the high and low affinity sites of SUR1/Kir6.2 with IC50 values of 0.95 and 100 nM, respectively.{60356}

• SKU: CAY33752-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 33752-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK