Formulation: A solid
Formal Name: (6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy-1,1,2,2-d4)phenyl)methanone hydrochloride
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C28H23D4NO4S • HCl
Formula Weight: 514,1
Shelf life (days): 1460
CAS Number: 1188263-47-9
Notes: Raloxifene-d4 is intended for use as an internal standard for the quantification of raloxifene (Item No. 10011620) by GC- or LC-MS. Raloxifene is a selective estrogen receptor modulator (SERM) that exhibits estrogenic activity in bone cells without stimulating breast or uterine tissues.{16603} Raloxifene guards endothelial cells obtained from rat aortic rings against oxidative insult (1 µM) and lowers serum cholesterol in ovariectomized rodents (ED50 = 0.2 mg/kg).{16602,16603} Formulations containing raloxifene have been shown to reduce bone resorption and promote bone formation in post-menopausal women.{16604}
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