RN-9893 (hydrochloride), CAS 2109450-40-8

Formulation: A solid

Formal Name: N-[4-[[4-(1-methylethyl)-1-piperazinyl]sulfonyl]phenyl]-2-nitro-4-(trifluoromethyl)-benzamide, monohydrochloride

Purity: ≥98%

Formula Markup: C21H23F3N4O5S • HCl

Formula Weight: 537

Shelf life (days): 1460

CAS Number: 2109450-40-8

Notes: RN-9893 is an antagonist of transient receptor potential vanilloid 4 (TRPV4; IC50s = 0.42 and 0.66 μM, respectively, for the human and rat receptors).{52086} It is selective for TRPV4 over TRPV1, TRPV3, and TRPM8 (IC50s = 10, >30, and 30 μM, respectively). RN-9893 reduces rat TRPV4 activity induced by 4α-phorbol 12,13-didecanoate (4α-PDD; Item No. 20446) or hypotonicity (IC50s = 0.57 and 2.1 μM, respectively, in cell free assays).

• SKU: CAY29172-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29172-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK