Formulation: A crystalline solid
Formal Name: (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide, monohydrochloride, monohydrate
Purity: ≥98%
Formula Markup: C17H26N2O • HCl [H2O]
Formula Weight: 328,9
Shelf life (days): 1460
CAS Number: 132112-35-7
Notes: (–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers.{33665} In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve.{42580} (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine (Item No. 16618).{42581} Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.
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