Formulation: A crystalline solid
Formal Name: (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-9-(1-oxopropoxy)-2H-naphtho[2,1-c]pyran-7-carboxylic acid, methyl ester
Purity: ≥98%
Formula Markup: C24H30O8
Formula Weight: 446,5
Shelf life (days): 730
CAS Number: 689295-71-4
Notes: Salvinorin A propionate is a selective partial agonist at κ1-opioid receptors (KOR) with a Ki value of 32.6 nM.{34652} It inhibits adenylate cyclase (EC50 = 4.7 nM) in HEK293 cells transfected with human KOR.{34651} It is selective for KORs over µ, δ, and ORL-1 opioid receptors and has no effect at serotonin, dopamine, muscarinic, or adrenergic receptors. In mice, salvinorin A propionate (13 µg, i.c.v.) reduces nociceptive responses in a radiant heat tail-flick assay, though not as potently as salvinorin A (Item No. 11487).{34652}
English
Deutsch
