SANT-2, CAS 329196-48-7

Formulation: A crystalline solid

Formal Name: N-[3-(1H-benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxy-benzamide

Purity: ≥98%

Formula Markup: C26H26ClN3O4

Formula Weight: 480

Shelf life (days): 1460

CAS Number: 329196-48-7

Notes: SANT-2 is a Smoothened (Smo) receptor antagonist.{21771,24191} It binds to the Smo receptor (Kd = 12 nM) and inhibits binding of the Smo receptor agonist SAG-1.3 (SAG; Item No. 11914) and antagonist cyclopamine (Item No. 11321) (Kis = 7.8 and 8.4 nM, respectively). SANT-2 inhibits hedgehog signaling induced by an N-terminal fragment of sonic hedgehog (Shh) in an Shh-LIGHT2 cellular assay (IC50 = 30 nM).{21771}

• SKU: CAY21208-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21208-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK